McKesson Clinical Reference Systems: Women's Health Advisor 2002.2
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What is secondary hypertension?

High blood pressure caused by a disease or another known medical problem is called secondary hypertension. Most cases of secondary hypertension are caused by kidney or hormonal problems.

Normal blood pressures average 120/80 ("120 over 80") but can rise and fall with exercise or rest. The pressures are measured in millimeters of mercury, with the upper number (120) being the pressure at the end of the heartbeat (systolic pressure). The lower number (80) is the pressure at the beginning of the heartbeat (diastolic pressure). If repeated checks of your blood pressure show that it is higher than 140/90, you have hypertension. If your blood pressure is between 120/80 and 140/90, you may need treatment for high blood pressure if you have other health problems, such as diabetes.

How does it occur?

Many medical conditions, diseases, and medicines can cause secondary hypertension, including:

• narrowing of the arteries in the kidneys
• narrowing of the aorta, a large blood vessel that supplies blood to the lower body
• several types of kidney disease
• excess secretion of a hormone called aldosterone from the adrenal gland
• tumor of the adrenal gland
• Cushing's syndrome, a disorder in which there is too much corticosteroid hormone in the blood
• medicines such as estrogen and oral contraceptives
• abuse of drugs such as amphetamines, alcohol, or diet pills
• pregnancy.

What are the symptoms?

High blood pressure may not cause any symptoms. Even secondary hypertension may have few symptoms. Symptoms are usually general and may include:

• headaches
• dizziness
• fatigue
• restlessness and sleeplessness
• nosebleeds
• palpitations or an awareness of your heartbeat
• general feeling of ill health
• the need to urinate often
• round or "moon" face, excess body and facial hair, and weight gain if the high blood pressure is caused by Cushing's syndrome.

How is it diagnosed?

Your health care provider will ask about your symptoms and will do a physical exam. Blood tests, chest x-rays, and an electrocardiogram may be done. Your provider will want to measure your blood pressure on three different days when you are relaxed and not in a hurry and have not had alcohol for 72 hours.

Your medical history is an important part of diagnosis. Your health care provider will ask about your personal and family history of high blood pressure and heart or kidney disease.

How is it treated?

Secondary hypertension is treated by treating the condition causing the high blood pressure. For example, if you have high blood pressure caused by Cushing's syndrome, treatment for Cushing's will lower your blood pressure.

Your health care provider may recommend additional treatments to lower your blood pressure, such as diuretics or other medicines that reduce blood pressure.

How long will the effects last?

If the cause can be diagnosed and treated, your blood pressure should improve. If you are taking medicine to reduce your blood pressure and your underlying condition is treated, you may be able to cut down or stop taking the blood pressure medicine.

How can I take care of myself?

• Always follow your health care provider's instructions for taking medicines. Don't take less medicine or stop taking medicine without talking to your provider first. It can be dangerous to suddenly stop taking blood pressure medicine. Also, do not increase your dosage of any medicine without first talking with your provider.
• Check your blood pressure (or have it checked) as often as your health care provider advises. Keep a chart of the readings.
• Don't smoke.
• Reduce the salt in your diet according to your health care provider's advice.
• With your provider's approval, start an exercise program that you can do regularly (such as biking or walking).
• Lose weight if you need to.
• Limit the amount of alcohol you drink.
• Try to reduce the stress in your life or learn how to deal better with situations that make you feel anxious.
• See your health care provider as often as he or she recommends.

What can be done to help prevent secondary hypertension?

Most of the conditions that cause secondary hypertension cannot be prevented. However, regular checkups can help detect many conditions before they become serious, including those that can result in high blood pressure.

This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.